Sepsis is a life-threatening condition that occurs when the body has an extreme and dysfunctional response to an infection, causing the immune system to injure a person's own tissues and organs instead of just fighting the infection[1][2][3][4][5].
This response leads to widespread inflammation, blood clotting, and reduced blood flow, which can result in damage to vital organs such as the lungs, kidneys, liver, and brain[2][6][4][5]. If sepsis becomes severe or is left untreated, it can progress to septic shock, which involves a dramatic drop in blood pressure and can quickly lead to organ failure and death[1][6][4].
Sepsis can arise from any type of infection—bacterial, viral, fungal, or parasitic—but is most commonly triggered by bacterial infections[2][6][5]. Common sources include lung infections (like pneumonia), urinary tract infections, abdominal infections, and skin infections[6][7].
Key symptoms may include:
- Fever, shivering, or feeling very cold
- Rapid heart rate
- Fast or difficult breathing
- Confusion or reduced alertness
- Clammy or sweaty skin
- Severe pain or discomfort
The risk for sepsis is higher in very young children, the elderly, people with chronic health conditions, and those with weakened immune systems[5][7]. Sepsis is a medical emergency; immediate medical attention is crucial for the best chance of survival[2][3][5].
Sepsis is not itself contagious, but the infections that cause it can be[8][6].
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- https://www.mayoclinic.org/diseases-conditions/sepsis/symptoms-causes/syc-20351214
- https://my.clevelandclinic.org/health/diseases/12361-sepsis
- https://www.sepsis.org/sepsis-basics/what-is-sepsis/
- https://en.wikipedia.org/wiki/Sepsis
- https://www.cdc.gov/sepsis/about/index.html
- https://www.webmd.com/a-to-z-guides/sepsis-septicemia-blood-infection
- https://www.hopkinsmedicine.org/health/conditions-and-diseases/septicemia
- https://www.sepsiscanada.ca/about/what-is-sepsis
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